Game 1: MLB All-Stars 3, NPB All-Stars 2

Jermaine Dye hit a two-run homer in the third off of Tetsuya Utsumi to make it 3-0 and that was all the MLB needed as John Lackey pitched five innings, allowing just one run on two hits. John Maine pitched two innings of relief and allowed one run on two hits. With the score 3-2 after the seventh, Scot Shields and Joe Nathan shut out the NPB All-Stars the rest of the way.

W - John Lackey (1-0)
L - Tetsuya Utsumi (0-1)
S - Joe Nathan (1)
HR - Jermaine Dye (1)